2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody[1].
Product Specifications
CAS Number
2964536-59-0
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-msp-5-ha-ggfg-nh-ch2-o-ch2-co-exatecan.html
Purity
98.27
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O
Molecular Formula
C53H55FN10O13S
Molecular Weight
1091.13
References & Citations
[1]Cai JQ, et al. Antibody against her3, conjugate and use thereof. WO2023143263A1. 2023-08-03.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Frequently Asked Questions
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