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2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan

Selected Variant

HY-157813-01

Size: 5 mg

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody[1].

Product Specifications

CAS Number

2964536-59-0

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-msp-5-ha-ggfg-nh-ch2-o-ch2-co-exatecan.html

Purity

98.27

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O

Molecular Formula

C53H55FN10O13S

Molecular Weight

1091.13

References & Citations

[1]Cai JQ, et al. Antibody against her3, conjugate and use thereof. WO2023143263A1. 2023-08-03.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Camptothecins

Available Sizes

Price

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