RIF1 rabbit pAb
Product Specifications
Gene ID
55183
UniProt
Q5UIP0
Cellular Locus
Nucleus. Chromosome. Chromosome, telomere. Cytoplasm, cytoskeleton, spindle. Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity). Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490). Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028). Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028)..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human RIF1 AA range: 1428-1478
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES19583-1.pdf
Subcellular Location
Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity) . Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490) . Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028) . Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028) . .
Gene ID (Human)
55183
SwissProt (Human)
Q5UIP0
Available Sizes
Curated Selection
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