RIF1 rabbit pAb

Product Specifications

UniProt

Q5UIP0

Swiss Prot

Q5UIP0

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human RIF1 AA range: 1428-1478

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity) . Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490) . Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028) . Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028) . .