RIF1 rabbit pAb
Product Specifications
UniProt
Q5UIP0
Swiss Prot
Q5UIP0
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human RIF1 AA range: 1428-1478
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle . Following interaction with TP53BP1, recruited to sites of DNA damage, such as DSBs (By similarity) . Exhibits ATM- and TP53BP1-dependent localization to uncapped or aberrant telomeres and to DNA double strand breaks (DSBs) (PubMed:15342490) . Does not associate with normal telomere structures (PubMed:15342490, PubMed:15583028) . Localizes to microtubules of the midzone of the mitotic spindle during anaphase, and to condensed chromosomes in telophase (PubMed:15583028) . .
Gene ID (Human)
55183
Available Sizes
Curated Selection
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