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Etentamig

Etentamig is a BCMA x CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases[1].

Product Specifications

CAS Number

2490552-52-6

Product Name Alternative

ABBV-383; TNB 383B

UNSPSC

12352203

Target

CD3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/abbv-383.html

Purity

99

Smiles

[Etentamig]

Molecular Weight

(123.8 kDa)

References & Citations

[1]D'Souza A, et al. A Phase I First-in-Human Study of ABBV-383, a B-Cell Maturation Antigen x CD3 Bispecific T-Cell Redirecting Antibody, in Patients With Relapsed/Refractory Multiple Myeloma. J Clin Oncol. 2022 Nov 1;40 (31) :3576-3586.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

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Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

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