Sarafotoxin S6c

<strong>Sarafotoxin S6c</strong> <strong>Catalog number:</strong> MDP0627 <strong>CAS Number: </strong>147859-80-1 <strong>Sequence: </strong>Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bonds between Cys1-Cys15 and Cys3-Cys11) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 2515.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Nayler WG, Gu XH, Casley DJ. Sarafotoxin S6c is a relatively weak displacer of specifically bound 125I-endothelin Biochem Biophys Res Commun. 1989 May 30;161(1):89-94. 2: Williams DL Jr, Jones KL, Pettibone DJ, Lis EV, Clineschmidt BV. Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes Biochem Biophys Res Commun. 1991 Mar 15;175(2):556-61. 3: Miasiro N, Karaki H, Paiva AC. Distinct endothelin-B receptors mediate the effects of sarafotoxin S6c and IRL1620 in the ileum J Cardiovasc Pharmacol. 1998;31 Suppl 1:S175-8. 4: Chabrier PE, Braquet P. Endothelin Horm Res. 1990;34(3-4):169-74. 5: Davenport AP, Maguire JJ. Endothelin Handb Exp Pharmacol. 2006;(176 Pt 1):295-329. 6: Cardozo AM, D'Orléans-Juste P, Bkaily G, Rae GA. Simultaneous changes in intracellular calcium and tension induced by endothelin-1 and sarafotoxin S6c in guinea pig isolated gallbladder: influence of indomethacin Can J Physiol Pharmacol. 2002 May;80(5):458-63. 7: Ducancel F. The sarafotoxins Toxicon. 2002 Nov;40(11):1541-5. 8: Matsuo G, Matsumura Y, Tadano K, Hashimoto T, Morimoto S. Effects of sarafotoxin S6c on renal haemodynamics and urine formation in anaesthetized dogs Clin Exp Pharmacol Physiol. 1997 Jul;24(7):487-91. 9: Takasaki C. [Sarafotoxin] Seikagaku. 1993 Mar;65(3):189-93. <a href="https://pubmed.ncbi.nlm.nih.gov/7706028">10: Haque MS, Taniguchi T, Sugiyama K, Okada K, Kitazawa Y. The ocular hypotensive effect of the ETB receptor selective agonist, sarafotoxin S6c, in rabbits Invest Ophthalmol Vis Sci. 1995 Apr;36(5):804-8.</a> <br><strong>Products Related to Sarafotoxin S6c can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>