RecombinantGRO-β/MIP-2/CXCL2, Rat
Rat CXCL2 also named CINC-3, is belonging to the CXC chemokine family. It is encoded by the gene CXCL2. CXCL2 shares 90% amino acid sequence with CXCL1/GROα. CINC-3 is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is expressed by cytokine-stimulated rat alveolar macrophages and fibroblasts. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. The amino acid sequence of rat CXCL2 is 88% identical to murine CXCL2.
Product Specifications
Product Name Alternative
Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, MIP-2, GRO2, CINC-3
Source
Escherichia coli.
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1 EU/μg of rRtMIP-2/CXCL2 as determined by LAL method.
Purity
>98% by SDS-PAGE and HPLC analyses.
Bioactivity
Form
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Molecular Weight
Approximately 7.9 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids.
Storage Conditions
Notes
For research use only.
Applications Notes
Preservative
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
AA Sequence
VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Vitamin D3 Sulfate Sodium Salt (Technical Grade)
