What is the catalog number for MeBIO?

The catalog number for MeBIO is HY-103221.

What sizes are available for MeBIO?

MeBIO is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg.

How many pack sizes does MeBIO come in?

MeBIO is available in 5 different pack sizes.

MeBIO is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MeBIO?

MeBIO is manufactured by QuantiMol.

What is the estimated delivery time for MeBIO?

Estimated delivery time for MeBIO is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MeBIO?

The safety data sheet for MeBIO is available here: http://file.medchemexpress.com/batch_PDF/HY-103221/MeBIO-SDS-MedChemExpress.pdf.

MeBIO

MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively[1].

Product Specifications

CAS Number

667463-95-8

UNSPSC

12352005

Hazard Statement

H228, H315, H319

Target

Aryl Hydrocarbon Receptor; CDK; GSK-3

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mebio.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 14.71 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N(C)C2=C(C=CC(Br)=C2)/C1=C3NC4=C(C=CC=C4)C/3=N\O

Molecular Formula

C17H12BrN3O2

Molecular Weight

370.20

Precautions

H228, H315, H319

References & Citations

[1]Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10 (12) :1255-66. |[2]Knockaert, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene 23.25 (2004) : 4400-4412.