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MeBIO

Product Specifications

UNSPSC Description

MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively[1].

Target Antigen

Aryl Hydrocarbon Receptor; CDK; GSK-3

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Immunology/Inflammation;PI3K/Akt/mTOR;Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mebio.html

Purity

98.0

Solubility

DMSO : 14.71 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C1N(C)C2=C(C=CC(Br)=C2)/C1=C3NC4=C(C=CC=C4)C/3=N\O

Molecular Weight

370.20

References & Citations

[1]Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66. |[2]Knockaert, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene 23.25 (2004): 4400-4412.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-103221/MeBIO-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-103221/MeBIO-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

667463-95-8

Available Sizes

Curated Selection

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