Telotristat
Telotristat (LP-778902) is a potent tryptophan hydroxylase inhibitor with an in vivo IC50 of 0.028 μM.
Product Specifications
CAS Number
1033805-28-5
Product Name Alternative
LP-778902
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Tryptophan Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/telotristat.html
Purity
99.42
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CC=C(C2=NC(N)=NC(O[C@H](C3=CC=C(Cl)C=C3N4N=C(C)C=C4)C(F)(F)F)=C2)C=C1)C(O)=O
Molecular Formula
C25H22ClF3N6O3
Molecular Weight
546.93
Precautions
H315, H319, H335
References & Citations
[1]Lapuerta P, et al. Telotristat etiprate, a novel inhibitor of serotonin synthesis for the treatment of carcinoid syndrome. Clin. Invest. (Lond.) (2015) 5 (5), 447–456|[2]US20080153852
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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