3-IN-PP1
3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer[1].
Product Specifications
CAS Number
2227110-54-3
UNSPSC
12352005
Target
PKD
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-in-pp1.html
Purity
99.37
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C2C(N(C(C)(C)C)N=C2C3=CNC4=C3C=CC=C4)=NC=N1
Molecular Formula
C17H18N6
Molecular Weight
306.37
References & Citations
[1]Philippe Gilles, et al. Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors. Eur J Med Chem
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKD1; PKD2; PKD3
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rat Phosphodiesterase 3B, cGMP Inhibited (PDE3B) ELISA Kit
Rat Phosphodiesterase 3B, cGMP Inhibited (PDE3B) ELISA Kit
![FOXP3 Recombinant Rabbit Monoclonal Antibody [JF0898]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea8290d/imageurl/et1702-12.webp)
FOXP3 Recombinant Rabbit Monoclonal Antibody [JF0898]
PDCD1 / PD1 / CD279 (Programmed Cell Death 1) (PDCD1/2720), CF647 conjugate, 0.1mg/mL
Biotin Conjugated Arum maculatum Lectin (Lords and Ladies) -AMA-
