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COX82 Rabbit pAb

The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from Cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008]

Synonyms

Cytochrome c oxidase subunit 8A, mitochondrial (Cytochrome c oxidase polypeptide VIII-liver/heart;Cytochrome c oxidase subunit 8-2)

Gene ID

1351

UniProt

P10176

Cellular Locus

Mitochondrion inner membrane ; Single-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human COX82 AA range: 10-90

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, ELISA

Validated Applications

IHC,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES17271-1.pdf

Subcellular Location

Mitochondrion inner membrane ; Single-pass membrane protein .

Other Product Names

Cytochrome c oxidase subunit 8A, mitochondrial (Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2)

Gene ID (Human)

1351

SwissProt (Human)

P10176

Available Sizes

Curated Selection

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