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BGN3

BGN3 is a good substrate for the SNAP-tag and H5 enzymes. The activities of SNAP-tag and H5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively) [1]. BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[1151762-33-2]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bgn3.html

Purity

99.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCC1=CC=C(COC2=C3C(NC=N3)=NC(N)=N2)C=C1

Molecular Formula

C13H12N8O

Molecular Weight

296.29

References & Citations

[1]Merlo R, et al. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. J Enzyme Inhib Med Chem. 2021;36 (1) :85-97.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139162/BGN3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139162/BGN3-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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