2',3'-Di-O-acetyl-D-uridine
2',3'-Di-O-acetyl-D-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[29108-90-5]
Product Name Alternative
Acetic acid 4-acetoxy-5- (2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl) -2-hydroxymethyl-tetrahydrofuran-3-yl ester
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-3-di-o-acetyl-d-uridine.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]1O[C@@H](N2C(NC(C=C2)=O)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O
Molecular Formula
C13H16N2O8
Molecular Weight
328.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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