Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MMPIP (hydrochloride)

MMPIP hydrochloride is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM) . MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice[1][2].

Product Specifications

CAS Number

1215566-78-1

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mmpip-hydrochloride.html

Purity

99.10

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(ON=C2C3=CC=NC=C3)C=C(C4=CC=C(OC)C=C4)N1C.[H]Cl

Molecular Formula

C19H16ClN3O3

Molecular Weight

369.80

References & Citations

[1]Gentaroh Suzuki, et al. In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists. J Pharmacol Exp Ther. 2007 Oct;323 (1) :147-56.|[2]Paulina Cieślik, et al. Negative Allosteric Modulators of mGlu 7 Receptor as Putative Antipsychotic Drugs. Front Mol Neurosci. 2018 Sep 20;11:316.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MGluR7

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SENP8 (Sentrin-specific Protease 8, Sentrin/SUMO-specific Protease SENP8, Deneddylase-1, DEN1, FKSG8, NEDD8-specific Protease 1, NEDP1, Protease, Cysteine 2, PRSC2) (MaxLight 405)
MBS6192531-01 0.1 mL

SENP8 (Sentrin-specific Protease 8, Sentrin/SUMO-specific Protease SENP8, Deneddylase-1, DEN1, FKSG8, NEDD8-specific Protease 1, NEDP1, Protease, Cysteine 2, PRSC2) (MaxLight 405)

Sign In for Pricing
View Details
SENP8 (Sentrin-specific Protease 8, Sentrin/SUMO-specific Protease SENP8, Deneddylase-1, DEN1, FKSG8, NEDD8-specific Protease 1, NEDP1, Protease, Cysteine 2, PRSC2) (MaxLight 405)
MBS6192531-02 5x 0.1 mL

SENP8 (Sentrin-specific Protease 8, Sentrin/SUMO-specific Protease SENP8, Deneddylase-1, DEN1, FKSG8, NEDD8-specific Protease 1, NEDP1, Protease, Cysteine 2, PRSC2) (MaxLight 405)

Sign In for Pricing
View Details
Rabbit Monoclonal FGF basic/FGF2/bFGF Antibody (013) [DyLight 488]
NBP2-89192G 0.1 mL

Rabbit Monoclonal FGF basic/FGF2/bFGF Antibody (013) [DyLight 488]

Sign In for Pricing
View Details
6330403K07Rik Mouse shRNA Lentiviral Particle (Locus ID 103712)
TL515603V 500 µL Each

6330403K07Rik Mouse shRNA Lentiviral Particle (Locus ID 103712)

Sign In for Pricing
View Details
FbxO6 Rabbit Polyclonal Antibody (BF680)
orb2400785 100 µL

FbxO6 Rabbit Polyclonal Antibody (BF680)

Sign In for Pricing
View Details
NFKBIL2 Lentiviral Activation Particles (h)
sc-410906-LAC 200 µL

NFKBIL2 Lentiviral Activation Particles (h)

Sign In for Pricing
View Details