Carlumab
Carlumab (CNTO 888) is a human anti-CCL2 (chemokine ligand 2) antibody with high affinity. Carlumab can be used in cancer research, particularly in prostate cancer[1].
Product Specifications
CAS Number
[915404-94-3]
Product Name Alternative
CNTO 888
UNSPSC
12352203
Target
CCR
Type
Inhibitory Antibodies
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carlumab.html
Purity
97.80
Solubility
10 mM in DMSO
Smiles
[Carlumab]
Molecular Weight
(144.87 kDa)
References & Citations
[1]Fetterly GJ, et al.. Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data. J Clin Pharmacol. 2013 Oct;53 (10) :1020-7.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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