Carlumab

Carlumab (CNTO 888) is a human anti-CCL2 (chemokine ligand 2) antibody with high affinity. Carlumab can be used in cancer research, particularly in prostate cancer[1].

Product Specifications

CAS Number

[915404-94-3]

Product Name Alternative

CNTO 888

UNSPSC

12352203

Target

CCR

Type

Inhibitory Antibodies

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/carlumab.html

Purity

97.80

Solubility

10 mM in DMSO

Smiles

[Carlumab]

Molecular Weight

(144.87 kDa)

References & Citations

[1]Fetterly GJ, et al.. Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data. J Clin Pharmacol. 2013 Oct;53 (10) :1020-7.