SNIPER (TACC3) -2
SNIPER (TACC3) -2 targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER (TACC3) -2 induces cancer cell death[1].
Product Specifications
UNSPSC
12352005
Target
SNIPERs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sniper-tacc3-2.html
Purity
99.54
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCNC([C@H](CC(C)C)NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)=O)C2=CC=C(C3=NC(CNC4=NC=CC(NCC(C)C)=N4)=CS3)C=C2
Molecular Formula
C43H61N9O7S
Molecular Weight
848.07
References & Citations
[1]Ohoka N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014 Nov 6;5:e1513.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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