SNIPER (TACC3) -2
SNIPER (TACC3) -2 targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER (TACC3) -2 induces cancer cell death[1].
Product Specifications
UNSPSC
12352005
Target
SNIPERs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sniper-tacc3-2.html
Purity
99.54
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCNC([C@H](CC(C)C)NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)=O)C2=CC=C(C3=NC(CNC4=NC=CC(NCC(C)C)=N4)=CS3)C=C2
Molecular Formula
C43H61N9O7S
Molecular Weight
848.07
References & Citations
[1]Ohoka N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014 Nov 6;5:e1513.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR224185L3V 200 µL
Senp3 (NM_030702) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details MR223253L3V 200 µL
Nectin3 (NM_021497) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details LV629479 1.0 µg DNA
Olr1148 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details bs-0229R-BF647 100 µL
FGF1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details 