What is the catalog number for Bradykinin?

The catalog number for Bradykinin is HY-P0206.

What sizes are available for Bradykinin?

Bradykinin is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Bradykinin come in?

Bradykinin is available in 6 different pack sizes.

Is Bradykinin in stock?

Bradykinin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bradykinin?

Bradykinin is manufactured by QuantiMol.

What is the estimated delivery time for Bradykinin?

Estimated delivery time for Bradykinin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bradykinin?

The safety data sheet for Bradykinin is available here: http://file.medchemexpress.com/batch_PDF/HY-P0206/Bradykinin-SDS-MedChemExpress.pdf.

Bradykinin

Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5].

Product Specifications

CAS Number

58-82-2

UNSPSC

12352209

Target

Bradykinin Receptor; Endogenous Metabolite; Ser/Thr Protease

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Bradykinin.html

Purity

99.93

Solubility

10 mM in DMSO|H2O : ≥ 100 mg/mL

Smiles

O=C(N1[C@@H](CCC1)C(NCC(N[C@H](C(N[C@@H](CO)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=CC=C4)=O)=O)[C@H]5N(CCC5)C([C@@H](N)CCCNC(N)=N)=O

Molecular Formula

C50H73N15O11

Molecular Weight

1060.21

References & Citations

[1]Hornig B, et al. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors inhumans. Circulation. 1997 Mar 4;95 (5) :1115-8.|[2]Wang G, et al. Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells. Oncol Rep. 2014 Oct;32 (4) :1709-14.|[3]Dong R, et al. Exogenous Bradykinin Inhibits Tissue Factor Induction and Deep Vein Thrombosis via Activating the eNOS/Phosphoinositide 3-Kinase/Akt Signaling Pathway. Cell Physiol Biochem. 2015;37 (4) :1592-606.|[4]Uchida S, et al. Afferent fibers involved in the bradykinin-induced cardiovascular reflexes from the ovary in rats. Auton Neurosci. 2015 Dec;193:57-62.|[5]Liu LT, et al. Effect of vascular bradykinin on pancreatic microcirculation and hemorheology in rats with severe acute pancreatitis. Eur Rev Med Pharmacol Sci. 2015;19 (14) :2646-50.