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WAY-200070

WAY-200070 is a selective estrogen receptor β (ERβ) agonist with an IC50 of 2.3 nM.

Product Specifications

CAS Number

440122-66-7

UNSPSC

12352005

Hazard Statement

H301, H319

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/WAY-200070.html

Purity

99.57

Solubility

DMSO : ≥ 31 mg/mL

Smiles

OC1=CC(Br)=C(OC(C2=CC=C(O)C=C2)=N3)C3=C1

Molecular Formula

C13H8BrNO3

Molecular Weight

306.11

Precautions

H301, H319

References & Citations

[1]Hughes ZA, et al. WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology. 2008 Jun;54 (7) :1136-42.|[2]Clipperton Allen AE, et al. Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice. Psychoneuroendocrinology. 2010 Aug;35 (7) :1008-22.|[3]Clipperton AE, et al. Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology. 2008 Sep;33 (10) :2362-75.|[4]Weiser MJ, et al. Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology. 2009 Apr;150 (4) :1817-25.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ERα; ERβ

Available Sizes

Frequently Asked Questions

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