DdCTP (trisodium)

DdCTP trisodium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP trisodium is a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV) . ddCTP trisodium can be used for AIDS research[1][2].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis; HIV Protease

Type

Oligonucleotides

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ddctp-trisodium.html

Concentration

100 mM * 50 μL in Water

Purity

98.03

Solubility

10 mM in DMSO

Smiles

O=[P](O[P](O[P](O)(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1CC[C@H](N2C(N=C(N)C=C2)=O)O1

Molecular Formula

C9H13N3Na3O12P3

Molecular Weight

517.10

References & Citations

[1]Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183 (2) :275-8.|[2]Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264 (5167) :1891-903.