Angiotensin I (human, mouse, rat)

Angiotensin I is a decapeptide hormone. Angiotensin I is the precursor of Angiotensin II (HY-13948) . Angiotensin I can be used in the study of cardiovascular diseases such as hypertension and vasospasm[1][2].

Product Specifications

CAS Number

[484-42-4]

UNSPSC

12352209

Target

Angiotensin-converting Enzyme (ACE) ; Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Angiotensin_1_Human.html

Purity

99.70

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@]([C@@H](C)CC)([H])C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC4=CNC=N4)=O)CC5=CC=CC=C5)=O)=O)=O)=O

Molecular Formula

C62H89N17O14

Molecular Weight

1296.48

References & Citations

[1]Manabe K, et al. Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. J Pharmacol Exp Ther. 1989 Oct;251 (1) :317-20.|[2]Kawaguchi H, et al. Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol. 1990 Aug;22 (8) :839-42.