1-Hydroxyoctadecane

1-Hydroxyoctadecane (Stearyl alcohol) is a long-chain fatty alcohol and excipient. 1-Hydroxyoctadecane forms a closed oil film, thereby reducing transepidermal water loss (TEWL) and promoting skin moisturization. 1-Hydroxyoctadecane improves Imiquimod (HY-B0180) -induced psoriatic skin inflammation in mice[1].

Product Specifications

CAS Number

[112-92-5]

Product Name Alternative

Stearyl alcohol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-hydroxyoctadecane.html

Purity

99.91

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCCCCO

Molecular Formula

C18H38O

Molecular Weight

270.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Dai YH, et al. Effect of stearyl alcohol on imiquimod-induced psoriasis-like skin inflammation in mice. Basic Clin Pharmacol Toxicol. 2024 Apr;134 (4) :498-506.