(R, R) -Secoisolariciresinol diglucoside

(R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells[1][2][3].

Product Specifications

CAS Number

[158932-33-3]

Product Name Alternative

(R, R) -SDG; (R, R) -LGM2605

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/r-r-secoisolariciresinol-diglucoside.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1C[C@@H](CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)[C@H](CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)CC4=CC(OC)=C(C=C4)O)=C(C=C1)O

Molecular Formula

C32H46O16

Molecular Weight

686.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Mishra OP, et al. Novel synthetic (S, S) and (R, R) -secoisolariciresinol diglucosides (SDGs) protect naked plasmid and genomic DNA From gamma radiation damage. Radiat Res. 2014 Jul;182 (1) :102-10.|[2]Mishra OP, et al. Synthesis and antioxidant evaluation of (S, S) - and (R, R) -secoisolariciresinol diglucosides (SDGs) . Bioorg Med Chem Lett. 2013 Oct 1;23 (19) :5325-8.|[3]Mishra OP, et al. Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochim Biophys Acta Gen Subj. 2018 Jun;1862 (6) :1364-1375.