Serabelisib
Serabelisib (MLN1117) is a selective p110α inhibitor with an IC50 of 15 nM.
Product Specifications
CAS Number
1268454-23-4
Product Name Alternative
MLN1117; INK1117; TAK-117
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MLN1117.html
Purity
99.44
Solubility
DMSO : 6.4 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5
Molecular Formula
C19H17N5O3
Molecular Weight
363.37
Precautions
H302, H315, H319, H335
References & Citations
[1]So L, et al. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function. J Biol Chem. 2013 Feb 22;288 (8) :5718-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471037-500 1x 500 µL
CD44 Standard (DF1485), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040745-100 1x 100 µL
CD45 / LCA (2B11 + PD7/26), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880669-500 1x 500 µL
P27 / KIP1 (SX53G8), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401081-500 1x 500 µL
CD45RO (190-2F2.5), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
