Serabelisib
Serabelisib (MLN1117) is a selective p110α inhibitor with an IC50 of 15 nM.
Product Specifications
CAS Number
[1268454-23-4]
Product Name Alternative
MLN1117; INK1117; TAK-117
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MLN1117.html
Purity
99.44
Solubility
DMSO : 6.4 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5
Molecular Formula
C19H17N5O3
Molecular Weight
363.37
Precautions
H302, H315, H319, H335
References & Citations
[1]So L, et al. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function. J Biol Chem. 2013 Feb 22;288 (8) :5718-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
Curated Selection
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