AMZ30
Product Specifications
UNSPSC Description
AMZ30 is a highly effective inhibitor of phosphatase PME-1 with an IC50 value of 600nM. It selectively reduces demethylated PP2A in cells.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/AMZ30.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC([N+]([O-])=O)=CC=C1)(N2C(/C=C(S(=O)(C3=CC=C(F)C=C3)=O)\C#N)=CC=C2)=O
Molecular Weight
461.44
References & Citations
[1]Bachovchin DA, et al. Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. J Med Chem. 2011 Jul 28;54(14):5229-36.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12833/AMZ30-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12833/AMZ30-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1313613-09-0
Available Sizes
Curated Selection
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