Antifungal agent 100

Antifungal agent 100 (compound 3i) exhibits significant antifungal effects against S. sclerotiorum with an EC50 value of 0.33 mg/L. Antifungal agent 100 displays an IC50 of 0.63 mg/mL against the Succinate dehydrogenase (SDH) of S. sclerotiorum[1].

Product Specifications

CAS Number

[2975157-18-5]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-209.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(C)C=C1)(NC2=CC=C(O3)C([C@@]4(C)[C@]3(N)C(C5=CC=CC=C5)=NO4)=C2)=O

Molecular Formula

C23H21N3O4S

Molecular Weight

435.50

References & Citations

[1]Yingkun Yan, et al. Design, Synthesis, Antifungal Activity, and Molecular Docking Studies of Novel Chiral Isoxazoline-Benzofuran-Sulfonamide Derivatives. J Agric Food Chem. 2024 Apr 15.