What is the catalog number for A 779?

The catalog number for A 779 is HY-P0216.

What sizes are available for A 779?

A 779 is available in the following size(s): 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.

How many pack sizes does A 779 come in?

A 779 is available in 5 different pack sizes.

A 779 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures A 779?

A 779 is manufactured by QuantiMol.

What is the estimated delivery time for A 779?

Estimated delivery time for A 779 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for A 779?

The safety data sheet for A 779 is available here: http://file.medchemexpress.com/batch_PDF/HY-P0216/A-779-SDS-MedChemExpress.pdf.

A 779

A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII.

Product Specifications

CAS Number

159432-28-7

UNSPSC

12352209

Target

Angiotensin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/A_779.html

Purity

99.12

Solubility

DMSO : 18.18 mg/mL (adjust pH to 2 with 1 M HCl)

Smiles

O=C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N[C@H](C)C(O)=O)=O)CC1=CNC=N1)=O)[C@@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2

Molecular Formula

C39H60N12O11

Molecular Weight

872.97

References & Citations

[1]Abuohashish HM, et al. Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis. Sci Rep. 2017 May 23;7 (1) :2293.|[2]Abuohashish HM, et al. ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats. Biomed Pharmacother. 2017 Aug;92:58-68.|[3]Yan WF, et al. Effects and related mechanism of angiotensin- (1-7) on Toll-like receptor 4-mediated oxidative stress in human umbilical vein endothelial cells. Zhonghua Xin Xue Guan Bing Za Zhi. 2017 Mar 24;45 (3) :223-229.