Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH
Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) [1].
Product Specifications
CAS Number
[2414254-47-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-gly-nh-ch2-o-cyclopropane-ch2cooh.html
Purity
97.44
Solubility
10 mM in DMSO
Smiles
O=C(NCC(NCOC(C1CC1)C(O)=O)=O)OCC2C3=C(C4=C2C=CC=C4)C=CC=C3
Molecular Formula
C23H24N2O6
Molecular Weight
424.45
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP2-59322AF700 100 µL
Mouse Monoclonal CACNA1G Antibody (S178A-9) [Alexa Fluor 700]
Ask
View Details 
MBS6123056-01 0.1 mL
Cytokeratin 8/18 (CARD2, CK8, CYK8, CYKER, Cytokeratin Endo A, DreK8, EndoA, K2C8, K8, Keratin 8, Krt 2.8, KRT8, Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18 Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18) (PE)
Ask
View Details 
MBS6123056-02 5x 0.1 mL
Cytokeratin 8/18 (CARD2, CK8, CYK8, CYKER, Cytokeratin Endo A, DreK8, EndoA, K2C8, K8, Keratin 8, Krt 2.8, KRT8, Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18 Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18) (PE)
Ask
View Details NBP3-20726R 0.1 mL
Mouse Monoclonal Cytokeratin 14 Antibody (rKRT14/8692) [DyLight 550]
Ask
View Details