Sulbutiamine

Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia.

Product Specifications

CAS Number

[3286-46-2]

Product Name Alternative

Bisibuthiamine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Sulbutiamine.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C/C(N(C=O)CC1=CN=C(C)N=C1N)=C(CCOC(C(C)C)=O)/SS/C(CCOC(C(C)C)=O)=C(C)\N(C=O)CC2=CN=C(C)N=C2N

Molecular Formula

C32H46N8O6S2

Molecular Weight

702.89

Precautions

H302, H315, H319, H335

References & Citations

[1]Kwag J, et al. Evidence for neuroprotective effect of sulbutiamine against oxygen-glucose deprivation in rat hippocampal CA1 pyramidal neurons. Biol Pharm Bull. 2011;34 (11) :1759-64.|[2]Kang KD, et al. Sulbutiamine counteracts trophic factor deprivation induced apoptotic cell death in transformed retinal ganglion cells. Neurochem Res. 2010 Nov;35 (11) :1828-39.