Sulbutiamine
Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia.
Product Specifications
CAS Number
3286-46-2
Product Name Alternative
Bisibuthiamine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Sulbutiamine.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(N(C=O)CC1=CN=C(C)N=C1N)=C(CCOC(C(C)C)=O)/SS/C(CCOC(C(C)C)=O)=C(C)\N(C=O)CC2=CN=C(C)N=C2N
Molecular Formula
C32H46N8O6S2
Molecular Weight
702.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Kwag J, et al. Evidence for neuroprotective effect of sulbutiamine against oxygen-glucose deprivation in rat hippocampal CA1 pyramidal neurons. Biol Pharm Bull. 2011;34 (11) :1759-64.|[2]Kang KD, et al. Sulbutiamine counteracts trophic factor deprivation induced apoptotic cell death in transformed retinal ganglion cells. Neurochem Res. 2010 Nov;35 (11) :1828-39.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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