3-O-Ethyl-L-ascorbic acid

3-O-Ethyl-L-ascorbic acid is a stable derivative of vitamin C and a cosmetic tyrosinase inhibitor. 3-O-Ethyl-L-ascorbic acid has antioxidant, anti-aging, and skin-whitening activities. 3-O-Ethyl-L-ascorbic acid is often used in the study of cosmetic[1][2][3].

Product Specifications

CAS Number

[86404-04-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-o-ethyl-l-ascorbic-acid.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@@H](CO)[C@](O1)([H])C(OCC)=C(O)C1=O

Molecular Formula

C8H12O6

Molecular Weight

204.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Wayne C Liao, et al. Antioxidant Ability and Stability Studies of 3- O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitor. J Cosmet Sci. Jul/Aug 2018;69 (4) :233-243.|[2]Fotis Iliopoulos, et al. 3-O-ethyl-l-ascorbic acid: Characterisation and investigation of single solvent systems for delivery to the skin. Int J Pharm X. 2019 Jul 19;1:100025.|[3]Zerbinati N, et al. The Anti-Ageing and Whitening Potential of a Cosmetic Serum Containing 3-O-ethyl-l-ascorbic Acid. Life (Basel) . 2021 Apr 29;11 (5) :406.