EV206
EV206 is a potent Hsp70 inhibitor. EV206 shows antiproliferative activity. EV206 induces apoptosis and increases the protein expression of cleaved PARP and caspase-3. EV206 shows antitumor activity[1].
Product Specifications
CAS Number
[2247047-81-8]
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ev206.html
Smiles
O=C1C2=C(C=CC=C2)N(CC=C)C(N1CC3)C4=C3C5=CC=CC=C5N4
Molecular Formula
C21H19N3O
Molecular Weight
329.40
References & Citations
[1]Min HY, et al. Development of a novel N14-substituted antitumor evodiamine derivative with inhibiting heat shock protein 70 in non-small cell lung cancer. Sci Rep. 2024 Oct 25;14 (1) :25436.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168566/EV206-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168566/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP70
Curated Selection
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