NCX 2121
NCX 2121 (NO-indomethacin) is an anti-inflammatory agent. NCX 2121 inhibits PaCa-2 cells growth witn an IC50 of 82 μM[1].
Product Specifications
CAS Number
[301838-28-8]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ncx-2121.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC=C(C=C2C(CC(SC[C@H](C(OCCCCO[N+]([O-])=O)=O)NC(C)=O)=O)=C1C)OC)C3=CC=C(Cl)C=C3
Molecular Formula
C28H30ClN3O9S
Molecular Weight
620.07
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Kashfi K, et al. Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect. J Pharmacol Exp Ther. 2002 Dec;303 (3) :1273-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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