GMP Human BMP-4 / BMP2B (improved sequence) Protein

GMP Human BMP-4 (improved sequence) Protein (GMP-BM4H18) is expressed from E. coli cells. It is a variant of BMP-4 to suit cell culture applications better.

Product Specifications

Background

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Specifications

This protein carries no "tag". The protein has a calculated MW of 13.2 kDa. The protein migrates as 13 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Expression Region

Ser 293 - Arg 408

Host

E. coli

Target

BMP-4

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

-20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution._x000D_Upon receipt, store it immediately at -20°C or lower for long term storage.