BD-9136
BD-9136 is a potent and highly selective BRD4 PROTAC depressant. BD-9136 has low-nanomolar degradation potencies against BRD4 , and its degradation selectivity for BRD4 is 1000 times that of BRD2 and BRD3 proteins. BD-9136 has antitumor activity[1]. (Pink: Desmethyl-QCA276 ; Black: 3- (2- (4-Methylpiperazin-1-yl) ethyl) azetidin-3-ol; Blue: Thalidomide-4-OH (HY-103596) )
Product Specifications
CAS Number
3037514-38-5
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bd-9136.html
Purity
98.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=NN=C2COCC(C(CC3=CC=CC=C3)=C(S4)C#CC5=CN(N=C5)C6(CCN7CCN(CC7)C)CN(C8=C(C9=CC=C8)C(N(C9=O)C%10CCC(NC%10=O)=O)=O)C6)=C4N21
Molecular Formula
C44H44N10O5S
Molecular Weight
824.95
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rat sC5b-9 (Soluble Terminal Complement Complex C5b-9) ELISA Kit
Rat sC5b-9 (Soluble Terminal Complement Complex C5b-9) ELISA Kit
Rat sC5b-9 (Soluble Terminal Complement Complex C5b-9) ELISA Kit
