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SCH-34826

SCH-34826 is an orally active neutral metalloendopeptidase (NEP) inhibitor that inhibits NEP and reduces the degradation of ANF, thereby enhancing its antihypertensive and diuretic effects. SCH-34826 can be used in the research of cardiovascular and renal diseases[1].

Product Specifications

CAS Number

105262-04-2

UNSPSC

12352005

Target

Neprilysin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease; Others

Assay Protocol

https://www.medchemexpress.com/sch-34826.html

Smiles

O=C(O)CCNC([C@H](CC1=CC=CC=C1)NC(CC2=CC=CC=C2)C(OCC3OC(C)(C)OC3)=O)=O

Molecular Formula

C27H34N2O7

Molecular Weight

498.57

References & Citations

[1]Sybertz E J, et al. Atrial natriuretic factor-potentiating and antihypertensive activity of SCH 34826. An orally active neutral metalloendopeptidase inhibitor[J]. Hypertension, 1990, 15 (2) : 152-161.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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