SCH-34826
SCH-34826 is an orally active neutral metalloendopeptidase (NEP) inhibitor that inhibits NEP and reduces the degradation of ANF, thereby enhancing its antihypertensive and diuretic effects. SCH-34826 can be used in the research of cardiovascular and renal diseases[1].
Product Specifications
CAS Number
105262-04-2
UNSPSC
12352005
Target
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/sch-34826.html
Smiles
O=C(O)CCNC([C@H](CC1=CC=CC=C1)NC(CC2=CC=CC=C2)C(OCC3OC(C)(C)OC3)=O)=O
Molecular Formula
C27H34N2O7
Molecular Weight
498.57
References & Citations
[1]Sybertz E J, et al. Atrial natriuretic factor-potentiating and antihypertensive activity of SCH 34826. An orally active neutral metalloendopeptidase inhibitor[J]. Hypertension, 1990, 15 (2) : 152-161.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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