GOAT-IN-1
GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.
Product Specifications
CAS Number
1452473-54-9
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/GOAT-IN-1.html
Purity
99.38
Solubility
DMSO : 150 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=NC(C(F)(F)F)=CC=C1COC2=CC(SC=C3CC(O)=O)=C3C(Cl)=C2
Molecular Formula
C18H13ClF3NO3S
Molecular Weight
415.81
References & Citations
[1]Nobuyuki Takakura, et al. WO 2013125732. 2013
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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