CPS-11
CPS-11 (N- (Hydroxymethyl) thalidomide) a Thalidomide analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB, activates NFAT, and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines[1][2][3].
Product Specifications
CAS Number
145945-21-7
Product Name Alternative
N- (Hydroxymethyl) thalidomide
UNSPSC
12352005
Target
NF-κB; Nuclear Factor of activated T Cells (NFAT) ; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cps-11.html
Purity
99.39
Smiles
O=C1N(C(C2=C1C=CC=C2)=O)C(C(N3CO)=O)CCC3=O
Molecular Formula
C14H12N2O5
Molecular Weight
288.26
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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