T-2307
Product Specifications
Product Name Alternative
Acriflavinium (chloride) 3,6-Acridinediamine mix
UNSPSC Description
T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including?Candida?species (MIC range, 0.00025 to 0.0078 μg/ml),?Cryptococcus neoformans?(MIC range, 0.0039 to 0.0625 μg/ml), and?Aspergillus?species (MIC range, 0.0156 to 4 μg/mL) [1].
Target Antigen
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t-2307.html
Purity
98.41
Solubility
DMSO : 50 mg/mL (ultrasonic;adjust pH to 3 with HCl)
Smiles
N=C(C1=CC=C(OCCCN2CCC(CCCOC3=CC=C(C(N)=N)C=C3)CC2)C=C1)N
Molecular Weight
437.58
References & Citations
[1]Junichi Mitsuyama, et al. In vitro and in vivo antifungal activities of T-2307, a novel arylamidine. Antimicrob Agents Chemother. 2008 Apr;52(4):1318-24.|[2]Eio Yamada, et al. T-2307 shows efficacy in a murine model of Candida glabrata infection despite in vitro trailing growth phenomena. Antimicrob Agents Chemother. 2010 Sep;54(9):3630-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114220/T-2307-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114220/T-2307-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
873546-31-7
Available Sizes
Curated Selection
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