3,4,5-Tricaffeoylquinic acid
Selected Variant
HY-N6588-01
Size: 1 mg
3,4,5-Tricaffeoylquinic acid (3,4,5-triCQA) inhibits tumor necrosis factor-α-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways. 3,4,5-Tricaffeoylquinic acid induces cell cycle arrest at G0/G1, actin cytoskeleton organization, chromatin remodeling, neuronal differentiation, and bone morphogenetic protein signaling in human neural stem cells. 3,4,5-Tricaffeoylquinic acid has the potential for the research of aging-associated diseases[1][2].
Product Specifications
CAS Number
86632-03-3
Product Name Alternative
3,4,5-triCQA
UNSPSC
12352005
Target
Akt; NF-κB
Type
Natural Products
Related Pathways
NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/3-4-5-tricaffeoylquinic-acid.html
Purity
98.71
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[C@H](OC(/C=C/C4=CC=C(O)C(O)=C4)=O)C1)O
Molecular Formula
C34H30O15
Molecular Weight
678.59
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
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