HA-CD44 interaction inhibitor 2
HA-CD44 interaction inhibitor 2 (compound 5) is a Hyaluronic acid (HA) -CD44 interaction inhibitor that effectively disrupts the integrity of cancer spheroids. HA-CD44 interaction inhibitor 2 also exhibits antiproliferative activity against cancer cells. HA-CD44 interaction inhibitor 2 inhibits MDA-MB-231 cells with EC50 value of 0.59 μM[1].
Product Specifications
CAS Number
3009761-01-4
UNSPSC
12352005
Target
Transmembrane Glycoprotein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-108.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=CC2=C1CCN(CC3=CC(OC)=C(OC)C(OC)=C3)C2
Molecular Formula
C19H23NO4
Molecular Weight
329.39
References & Citations
[1]Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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