Revusiran (sodium)

Revusiran sodium is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran sodium can be used for transthyretin (TTR) -mediated amyloidosis research[1].

Product Specifications

Product Name Alternative

ALN-TTRSC (sodium)

UNSPSC

12352208

Target

Small Interfering RNA (siRNA) ; Transthyretin (TTR)

Type

Oligonucleotides

Related Pathways

Epigenetics; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/revusiran-sodium.html

Purity

93.16

Solubility

10 mM in H2O

Smiles

[Revusiran(sodium)]

Molecular Weight

16121 (free acid)

References & Citations

[1]Jessica E Sutherland, et al. Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis. Nucleic Acid Ther. 2020 Feb;30 (1) :33-49.