Mc-Val-Cit-PAB-Gefitinib (chloride)
Mc-Val-Cit-PAB-Gefitinib chloride is a agent-linker conjugates for ADC. Mc-Val-Cit-PAB-Gefitinib chloride consists of Gefitinib (HY-50895) (an EGFR tyrosine kinase inhibitor) and the ADC linker Mc-Val-Cit-PAB[1].
Product Specifications
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-gefitinib-chloride.html
Purity
98.69
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
COC1=CC2=C(C=C1OCCCN3CCOCC3)C(NC(C=C4)=CC(Cl)=C4F)=NC=[N+]2CC(C=C5)=CC=C5NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN(C6=O)C(C=C6)=O)=O)=O)=O.[Cl-]
Molecular Formula
C50H63Cl2FN10O9
Molecular Weight
1038.00
References & Citations
[1]FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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