Esonarimod

Esonarimod (KE-298) is an antirheumatic agent.

Product Specifications

CAS Number

[101973-77-7]

Product Name Alternative

KE-298

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Esonarimod.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=C(C(CC(CSC(C)=O)C(O)=O)=O)C=C1

Molecular Formula

C14H16O4S

Molecular Weight

280.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Inoue T, et al. KE-298 and its active metabolite KE-758 suppress nitric oxide production by murine macrophage cells and peritoneal cells from rats with adjuvant induced arthritis. J Rheumatol. 2001 Jun;28 (6) :1229-37.|[2]Hasegawa M, et al. Formation of a disulfide protein conjugate of the SH-group-containing metabolite (M-I) ofesonarimod (KE-298) and its elimination in rats. J Pharm Pharmacol. 2002 Apr;54 (4) :493-8.