Esonarimod
Esonarimod (KE-298) is an antirheumatic agent.
Product Specifications
CAS Number
101973-77-7
Product Name Alternative
KE-298
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Esonarimod.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C(CC(CSC(C)=O)C(O)=O)=O)C=C1
Molecular Formula
C14H16O4S
Molecular Weight
280.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Inoue T, et al. KE-298 and its active metabolite KE-758 suppress nitric oxide production by murine macrophage cells and peritoneal cells from rats with adjuvant induced arthritis. J Rheumatol. 2001 Jun;28 (6) :1229-37.|[2]Hasegawa M, et al. Formation of a disulfide protein conjugate of the SH-group-containing metabolite (M-I) ofesonarimod (KE-298) and its elimination in rats. J Pharm Pharmacol. 2002 Apr;54 (4) :493-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
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