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5-Aminolevulinic acid-13C-1 (hydrochloride)

Product Specifications

UNSPSC Description

5-Aminolevulinic acid-13C-1 (5-ALA-13C-1) hydrochloride is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].

Target Antigen

Apoptosis; Autophagy; Endogenous Metabolite; Mitophagy

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis;Autophagy;Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5-aminolevulinic-acid-13c-1-hydrochloride.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(CC[13C](CN)=O)=O.Cl

Molecular Weight

168.58

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.|[3]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0305S3/5-Aminolevulinic-acid-13C-1-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0305S3/5-Aminolevulinic-acid-13C-1-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

129720-94-1

Available Sizes

Curated Selection

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