5-Aminolevulinic acid-13C-1 (hydrochloride)
Product Specifications
UNSPSC Description
5-Aminolevulinic acid-13C-1 (5-ALA-13C-1) hydrochloride is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].
Target Antigen
Apoptosis; Autophagy; Endogenous Metabolite; Mitophagy
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Autophagy;Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-aminolevulinic-acid-13c-1-hydrochloride.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC(CC[13C](CN)=O)=O.Cl
Molecular Weight
168.58
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.|[3]Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0305S3/5-Aminolevulinic-acid-13C-1-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0305S3/5-Aminolevulinic-acid-13C-1-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
129720-94-1
Available Sizes
Curated Selection
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