Cucurbitacin IIa
Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].
Product Specifications
CAS Number
[58546-34-2]
Product Name Alternative
Hemslecin A
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Survivin
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cucurbitacin-iia.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]([C@@](CC=C1[C@@]2([H])C[C@H](O)[C@@H](O)C1(C)C)([H])[C@@]2(C)C3=O)(C[C@@H](O)[C@]4([H])[C@@](C)(O)C(CCC(C)(C)OC(C)=O)=O)[C@@]4(C3)C
Molecular Formula
C32H50O8
Molecular Weight
562.73
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
CD45 (B220, CD45R, GP180, Leukocyte common antigen, LCA, Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C, PTPRC, Receptor-type tyrosine-Protein phosphatase C, T200 GlycoProtein) (MaxLight 750) discontinued
