Scopoletin

Scopoletin is an inhibitor of acetylcholinesterase (AChE) .

Product Specifications

CAS Number

[92-61-5]

Product Name Alternative

Gelseminic acid; Chrysatropic acid

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Apoptosis; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Scopoletin.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=CC(OC)=C(O)C=C2O1

Molecular Formula

C10H8O4

Molecular Weight

192.17

Precautions

H302

References & Citations

[1]Hornick A, et al. The coumarin Scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory. Neuroscience. 2011 Dec 1;197:280-92.|[2]Liu XL, et al. Effect of Scopoletin on PC3 cell proliferation and apoptosis. Acta Pharmacol Sin. 2001 Oct;22 (10) :929-33.