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Macropa-NH2 (TFA)

Product Specifications

CAS Number

2705054-08-4

UNSPSC Description

Macropa-NH2 TFA is the precursor of Macropa-NCS. Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/macropa-nh2-tfa.html

Purity

98.03

Solubility

DMSO : ≥ 130 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1.O=C(O)C(F)(F)F

Molecular Weight

661.62

References & Citations

[1]Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017;56(46):14712-14717.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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